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Cystitis
Cystitis is an infection of the bladder, but the term is often used indiscriminately and covers a range of infections and irritations in the lower urinary system. It causes burning sensations during urination and a frequent need to urinate.
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About the condition
Cystitis
Cystitis is an infection of the bladder, but the term is often used indiscriminately and covers a range of infections and irritations in the lower urinary system. It causes burning sensations during urination and a frequent need to urinate.
How you can get Cystitis
Infection from intestinal bacteria is by far the most frequent cause of cystitis, especially among women, who have a very short urethra (the tube through which the urine passes from the bladder to the outside). Normally, urine is sterile (there are no micro-organisms such as bacteria present). Between 20 to 40 per cent of women will get cystitis in their lifetime.
However, it is possible to have bacteria in the bladder without having any symptoms (especially in the elderly). There can be several reasons for the bacteria settling in the bladder. Inadequate emptying resulting in stagnation of urine may lead to infection. This may be caused by some drugs (for example, antidepressants), immobility, abnormal bladder control and constipation. Even the small drop which is always left behind may contain bacteria. Conditions that may make it easier for the bacteria to travel through the urethra include those listed below.
Toilet hygiene
Particularly common among females, as they have a shorter urethra than males and it is situated relatively close to their anus (back passage). Women and girls must dry themselves from front to back, towards the anus - not the other way around - to avoid leading bacteria from their intestine into their urethra.
Congenital deformity in the urinary system
In the case of repeated infections of the urinary system, particularly among boys and young men, the individual should be checked for a congenital (present from birth) deformity somewhere in the urinary system which prevents the complete emptying of the bladder.
People with a catheter
Everyone with a catheter (to drain urine) will have bacteria in their bladder, usually without symptoms. During the change of catheter, small lesions (damaged areas) may appear, which may increase the danger of infection (cystitis) and possible blood infection.
Men with an enlarged prostate
An enlarged prostate (male sex gland) in teh older male prevents the bladder from emptying completely.
Other conditions like prostatitis (infection in the prostate) and urethritis (infection in the urethra) may give rise to similar symptoms in the younger male.
Other causes
'Honeymoon' cystitis
Cystitis in women related to increased frequency of sexual activity.
Venereal diseases
Gonorrhoea and chlamydia infections may cause symptoms similar to cystitis. In addition, there is usually a vaginal discharge, bleeding after sexual intercourse and an inflamed cervix. Cystitis-like symptoms among young sexually active men may be caused by venereal diseases and they should seek immediate medical advice.
Parasites
Particularly among people who have been in North Africa or the Middle East. The bladder may be infested by parasites - schistosomiasis or bilharzia (river blindness). The symptoms are similar to cystitis, but there are no bacteria in the urine.
Postmenopausal women
Due to lack of female sex hormones in postmenopausal women, a range of changes take place in the whole body. A consequence of this is that the urinary system is more easily irritated by cystitis.
Contact dermatitis
Women using a deodorant or other potentially irritating material on their genitals may develop cystitis-like symptoms.
Symptoms
* Burning sensations or pain during urination.
* Frequent urination.
* Cloudy and foul-smelling urine.
* Pain directly above the pubic bone.
* Children under five years of age often have less concrete symptoms, such as weakness, irritability, reduced appetite and vomiting.
* Older women may also have no symptoms other than weakness, falls, confusion or fever.
* Occasional blood in the urine.
Advice
It is important to drink sufficiently, so the bladder is flushed thoroughly.
During urination the bladder should be emptied completely. It is a bad habit to sit on the toilet bent forward and reading while urinating.
A trick is to place yourself backwards on the toilet, so you lean against the wall. This posture is more suitable in securing a complete emptying of the bladder than the usual sitting posture.
Warm clothes on the lower part of the body will also help prevent cystitis.
As a prevention, it may be helpful to drink cranberry juice every day or take capsules. There is no doubt that this simple and natural treatment may help to reduce the frequency of recurrent infections. It is thought that the cranberry juice works by preventing common bacteria from ‘sticking’ to the walls of the bladder and so preventing infection taking hold.
Urination immediately after sexual intercourse will flush out most bacteria from the urethra.
Try to urinate at least once every three hours. Women who avoid urination for long periods suffer from more infections of the urinary system.
About the Medicine
About Trimethoprim
Trimethoprim is a type of medicine called an antibiotic. It is used to treat infections with bacteria.
In order to grow and multiply in numbers, bacterial cells need to produce genetic material (DNA). To produce DNA they require folic acid (folate). However, bacterial cells can't take up folic acid supplied in the diet like human cells can. Instead, they synthesise it themselves.
Trimethoprim works by preventing the bacteria from producing folate. Without folate, the bacteria cannot produce DNA and so are unable to increase in numbers. Trimethoprim therefore stops the spread of infection. The remaining bacteria are killed by the immune system or eventually die.
Side Effects
Medicines and their possible side effects can affect individual people in different ways. The following are some of the side effects that are known to be associated with this medicine. Because a side effect is stated here, it does not mean that all people using this medicine will experience that or any side effect.
* Nausea and vomiting
* Rash
* Itching (pruritus)
* Increase in the level of potassium in the blood (hyperkalaemia)
* Disturbance in the production of blood cells (see warning above)
* Abnormal reaction of the skin to light, usually a rash (photosensitivity)
* Severe skin rashes (eg erythema multiforme, toxic epidermal necrolysis)
The side effects listed above may not include all of the side effects reported by the drug's manufacturer.
Contraception and Trimethoprim
When taking antibiotic the oral contraceptive pill may be ineffective. You should continue taking the pill and use alternative contraception whilst you take Trimethoprim and for a week after stopping.
Important
There may be an increased risk of side effects on the kidney if this medicine is taken in combination with ciclosporin.
If this medicine is taken with the antimalarial pyrimethamine, the level of folic acid in the blood may decrease, which could cause folate deficiency anaemia or decreased production of blood cells.
This medicine may increase the blood level of the following medicines and could increase the risk of their side effects:
* dapsone
* digoxin
* phenytoin
* procainamide.
There is an increased risk of serious side effects on the blood cells if this medicine is used in combination with the following medicines:
This medicine may enhance the anti-blood-clotting effect of anticoagulant medicines such as warfarin. As this may increase the risk of bleeding, people who are taking an anticoagulant medicine should have their blood clotting time monitored more frequently while taking this medicine.
Manufacturers and Brands
Sandoz is a global generics leader. We save and improve lives by developing, producing and distributing high-quality, affordable pharmaceuticals. Thanks to our global network, Sandoz medicines are now available to 90% of people worldwide. In addition to direct cost savings to patients, we contribute to the stability of healthcare systems worldwide and free up resources for new and innovative medicines.
Teva UK Limited is one of the biggest pharmaceutical companies in the UK. We're proud to be part of the Teva Pharmaceutical Industries group, and we make medicines that help improve lives.
Actavis is one of the world's leading players in the development, manufacture, and sale of first-class generic pharmaceuticals.
Actavis has one of the broadest product portfolios and pipelines in the industry, with over 350 medicines available in the United Kingdom and more than 350 in development.
Product information leaflet
Click on the button below to read the Information Leaflet. Do not exceed the stated dose.
These leaflets are provided for information only and should not be used for treatment or in contradiction with your Doctor or Pharmacist's advice. One Click Doctor will do its best to keep these leaflets up-to-date but will not accept liability for out of date leaflets. You need to refer to the leaflets in the packaging for the latest manufacturer's information.
Choose your preferred medicine (Please pick one option only!)
Trimethoprim 200mg - 12 tablets (2 course treatment)
Trimethoprim works by preventing the bacteria from producing folate. Without folate, the bacteria cannot produce DNA and so are unable to increase in numbers. Trimethoprim ... read more. Size: 12 tablets Max Quantity allowed to purchase: 1 Collect 11 points with this purchase!
£10.50 RRP: £14.99
Trimethoprim 200mg - 6 tablets (1 course treatment)
Trimethoprim works by preventing the bacteria from producing folate. Without folate, the bacteria cannot produce DNA and so are unable to increase in numbers. Trimethoprim ... read more. Size: 6 tablets Max Quantity allowed to purchase: 1 Collect 8 points with this purchase!
£8.40 RRP: £8.99
The products below can be bought from OneClickPharmacy without a prescription
Canesten Oasis For Cystitis Cranberry
For the relief of the symptoms of cystitis.
Cystitis is an inflammation of the bladder, which causes painful irritation and an unpleasant burning sens... read more. Size: 6 Sachets Collect 4 points with this purchase!
£4.12 RRP: £5.77
Cystitis Relief For relief of the symptoms of cystitis in women. read more. Size: 6 powder Collect 4 points with this purchase!
Vantage Cystitis Relief Sachets x 6 Save over £2 on high street chemist prices. Cystitis Relief Sachets are for the relief of symptoms of cystitis in women only. Cystitis Relief Sachets contains similar ingred... read more. Size: 6 Sachets Collect 3 points with this purchase!
£2.92 RRP: £4.94
Canesten Oasis For Cystitis Cranberry
For the relief of the symptoms of cystitis.
Cystitis is an inflammation of the bladder, which causes painful irritation and an unpleasant burning sens... read more. Size: 6 Sachets Collect 4 points with this purchase!
£4.12 RRP: £5.77
Cystitis Relief For relief of the symptoms of cystitis in women. read more. Size: 6 powder Collect 4 points with this purchase!
Vantage Cystitis Relief Sachets x 6 Save over £2 on high street chemist prices. Cystitis Relief Sachets are for the relief of symptoms of cystitis in women only. Cystitis Relief Sachets contains similar ingred... read more. Size: 6 Sachets Collect 3 points with this purchase!
OneClickPharmacy is a GPhC registered online pharmacy, offering prescriptions, medicines and thousands of other health & beauty products at up to 90% off. OneClickPharmacy provides information only and is not a substitute for professional medical help. OneClickPharmacy recommend that you carefully read the information leaflets provided with your medication. You should always seek help from your doctor if you are currently being treated for any conditions and you should always inform your doctor and chemist/pharmacist of any medication you are taking. If you feel that you require further help, contact our online pharmacy team on 0844 44 11 800. Please see our Terms and Conditions for more information.
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