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1) Read all the information below including the Patient Information Leaflet.
2) Select the medicine you want to try.
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4) Answer all medical questions during checkout before paying and then a doctor will inform you of his decision.
Please read all the information below (sections 1 to 5) before placing an order, it is very important and you must not skip this step.
Jet Lag
Jet lag is a common condition that sometimes occurs after long distance flights. It is the result of your body finding it difficult to adjust to a new time zone.
Jet lag can disturb your sleep pattern and make you feel drowsy and lethargic (lacking in energy). Jet lag often becomes more severe as more time zones are crossed
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About the condition
Jet Lag
The world is divided into 24 time zones. The base is the Greenwich Meridian (an imaginary line that passes through Greenwich, London, and is used to help measure longitude). The clock changes by one hour for every 15º travelled in either direction from the Greenwich Meridian.
Jet lag occurs after crossing a number of time zones, which disrupts the body's normal ‘circadian rhythm’ (your body's natural 24-hour routine). This ‘biological clock’ or ‘body clock’ controls when you need to sleep and when you are awake. It also affects:
- hunger
- digestion
- bowel habits
- urine production
- body temperature
- blood pressure
Your biological clock is usually synchronised with your local time so that you feel hungry in the morning and sleepy in the evening. However, after travelling across time zones, your body takes a while to adjust to a new daily routine.
See Jet lag - causes for more information about the circadian rhythm and the biological clock.
Who gets Jet Lag?
Anyone can get jet lag, regardless of how often they travel by plane. People of any age can develop jet lag, but it is more common in people who are above 60.
Jet lag is thought to be less common in children and babies. However, there is not enough clear evidence to estimate how many children and babies are affected.
Symptoms of Jet Lag
A disturbed sleep pattern is one of the most common symptoms of jet lag. Although jet lag can make you tired, you may find it difficult to sleep at the correct times. For example, you may be awake during the night and sleep during the day.
As well as disturbed sleep, other symptoms of jet lag can include:
- indigestion
- constipation
- diarrhoea
- nausea
- loss of appetite
- difficulty concentrating
- feeling disorientated
- anxiety
- irritability
- memory problems
- clumsiness
- lack of energy
- light headedness
- confusion
- headaches
- sweating
- muscle soreness
- menstrual irregularities in women who often travel
- generally feeling unwell
The symptoms of jet lag will usually last for a few days (without treatment), depending on how quickly your body can adjust to the new time zone.
Causes of Jet Lag?
Circadian rhythm
Your circadian rhythm is your body's natural 24-hour routine, which is driven by a number of ‘biological clocks’ in your body. Jet lag occurs when your body's circadian rhythm is disrupted.
The biological clocks are found throughout your body and are made up of groups of cells that interact with each other. These cells are controlled by a ‘master clock’ in your brain that keeps the body clocks synchronised with one another.
Your body is used to a regular routine of light and darkness at certain times of the day. However, when you travel to a new time zone, the regular rhythm becomes disrupted.
Modern air travel makes it possible for you to travel across several different time zones in just a few of hours. As a result of travelling so quickly, your body has to catch up and re-establish its circadian rhythm. It takes time for your body to adjust to new times of light, darkness and eating. Your body may also have to adjust to differences in temperature.
Oxygen levels
The oxygen levels in an aeroplane cabin are also thought to play a role in jet lag. As the air pressure in an aeroplane cabin is relatively low, the amount of oxygen that you have in your blood is reduced.
A reduced amount of oxygen can affect your physical and mental abilities. For example, it can make you feel lethargic (lacking in energy) and dehydrated.
People with conditions such as heart disease, lung disease or anaemia (where the red blood cells are not able to carry enough oxygen), may be more severely affected by the reduced amount of oxygen inside the cabin.
East and west
The symptoms of jet lag are usually more obvious when you travel east rather than west. This is because your body finds it easier to adapt to a slightly longer day (in the west) than a slightly shorter one (in the east).
Your body adapts better when travelling west because you are extending your day, rather than travelling east when you are shortening it. Therefore, you usually find it easier to delay sleep for a few hours than trying to force yourself to sleep when you are not ready to.
Sleep routine
People who stick to a strict sleep routine – for example, those who go to bed at the same time each night – are more likely to be affected by jet lag.
Babies and children can sleep at any time of the day, so they tend to adjust to new time zones more easily, and are less likely to experience jet lag.
Other factors
A number of other factors can increase your likelihood of getting jet lag, or increase the severity of your symptoms. These factors include:
- dehydration (not drinking enough fluids)
- lack of sleep
- drinking alcohol
- stress
- being above 60 years of age increases the time it takes to recover from jet lag
About the Medicine
About Melatonin
Melatonin is a hormone that your body releases in the evening. It is a way of telling your brain that it is time for your body to sleep.
Your body clock is controlled by natural daylight and by the melatonin released in your body. Your body naturally produces melatonin when it gets darker in order to prepare your body for sleep. It stops producing the hormone when it gets light in order to help you wake up.
Some jet lag remedies contain melatonin to help you sleep at night when your body is finding it difficult to adjust to the new time zone.
However, there is currently inconclusive evidence as to whether melatonin supplements are effective. Although some people find them helpful, they are not currently licensed to prevent jet lag in the UK.
There is also insufficient evidence on melatonin's possible side effects on people who are taking the blood-thinning medicine called warfarin, or those with epilepsy (a condition that causes people to have repeated fits or seizures).
If you are considering taking a jet lag remedy that contains melatonin, talk to your GP first. They can advise you on whether it is suitable for you.
Side Effects
Although uncommon, allergic reactions to melatonin have been reported. Stop taking melatonin and seek emergency medical attention if you experience symptoms of a serious allergic reaction including difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives.
Other less serious side effects have also been reported. Talk to your doctor or pharmacist if you experience
- headache;
- drowsiness; or
- stomach upset.
Dosage
Take this medicine according to the enclosed patient information leaflet.
Advice
You can minimise the effects of jet lag by following the advice outlined below. When you arrive at your destination, you should:
- establish a new routine and try to get used to it as quickly as possible. This means eating meals and sleeping at the correct times for your new time zone, and not at the time you would usually eat and sleep at home
- avoid napping as soon as you arrive at your destination. Even if you are tired after a long flight, try to stay active until it is the correct time to sleep. This will help your body adjust more quickly
- spend time outdoors - do this as much as you can because natural light will help your body to adjust to a new routine.
Before travelling, contact your GP or pharmacist if you need to take certain medicines at specific times each day, for example, oral contraceptives or insulin. They can help you to work out when to take the medication upon arriving in your new time zone
Before you travel
Before travelling, you should:
- Change your sleep routine a few days before you are due to travel. If you are travelling east, go to bed an hour earlier than your usual time. If you are travelling west, go to bed an hour later. Try to adapt your sleeping routine with your destination in mind.
- Get enough sleep before you are due to travel. Flying when you are tired can make jet lag worse.
- Keep calm - airports can sometimes be stressful situations. Keep as calm and relaxed as possible because being stressed can make jet lag worse.
- Check in online - this can help to reduce stress and will enable you to relax as soon as you arrive at the airport.
During the flight
During the flight, you should:
- Drink plenty of fluid - also ensure that you are well hydrated before and after your flight.
- Rest during the flight by taking short naps.
- Limit caffeine consumption - do not consume too many drinks that contain caffeine (coffee, tea and cola), and avoid caffeinated drinks within a few hours of planned sleep.
- Avoid alcohol - eat light meals and avoid drinking alcohol because it can make the symptoms of jet lag worse.
- Keep active - if you are flying long distances, walk around the cabin occasionally and regularly stretch your arms and legs when you are sitting down. This will also help to reduce the risk of developing a potentially serious condition called deep vein thrombosis (DVT).
- Change your watch when you board the plane so that it matches the time of your destination. This will help you to adjust to your new time zone more quickly.
- Get some sleep - if it is night time at your destination, try to get some sleep. You may find ear plugs or eye masks useful.
Manufacturers and Brands
H. Lundbeck A/S and Neurim Pharmaceuticals Ltd. today announced that Lundbeck has in-licensed the exclusive rights for Circadin® for the treatment of primary insomnia for the majority of markets in Europe including the five major markets. Furthermore, Lundbeck holds the exclusive option to evaluate commercialization in markets outside of Europe.
Product information leaflet
Click on the button below to read the Information Leaflet. Do not exceed the stated dose.
These leaflets are provided for information only and should not be used for treatment or in contradiction with your Doctor or Pharmacist's advice. One Click Doctor will do its best to keep these leaflets up-to-date but will not accept liability for out of date leaflets. You need to refer to the leaflets in the packaging for the latest manufacturer's information.
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